Friday, December 16, 2005

Medline Article Cita

Medline Article Citations

There are hundreds of articles about hexachlorophene cited in Pub Med.Since hexachlorophene (commonly known by one of its brand names, PhiSoHex) is effectively used to combat the bacteria staphylococcus, many of the citations concern this use.
However you can also see many of the hexachlorophene citations in the area of its toxicology. Particularly in the 60s and 70s, both human and animal research began to show the toxicological mechanisms of hexachlorophene. It should be noted that the accumulation of this research and the abnormalities of the autopsies of babies resulted in the severe restrictions on the use of hexachlorophene. Below are just a few of the numbers of relevant hexachlorophene citations.

National Library of Medicine Gateway listings:
In their search of Medline/Pub Med journal citations and abstracts they found 1207.
In their search of TOXLINE for toxicology citations they found 276.
In their search of DART for developmental and reproductive toxicology articles they found 65 citations.

Within Medline/PubMed one must be careful to note that the mere search for a word like hexachlorophene will turn up citations of articles where hexachlorophene is only a side issue. The same is especially true when hexachlorophene is one of two search words. Even so, it might be helpful to start an investigation of hexachlorophene’s toxicological effects by noting this: hexachlorophene with liver occurs in 70 articles; hexachlorophene with brain occurs in 113 articles; hexachlorophene and myelin occurs in 41 articles. I've noted in prior posts that some of the articles in each of these areas do indicate hexachlorophene toxicological effects in both animal and human studies.

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