Thursday, February 16, 2006

BRAIN IMGING OF THE EFFECTS OF HEXACHLOROPHENE

I advocate the updating of hexachlorophene toxicity research by using the most appropriate advanced brain imaging technology. It is the purpose of this blog to raise questions about hexachlorophene on those babies who lived. This needs to be done with an open mind. We who were exposed to hexachlorophene , however, need to know more about its current effects on the white matter/ myelin of our central nervous system. My own library research is meant to raise necessary questions and suggest testable hypotheses. I do this in the hope that researchers whith more specific expertise become interested -- and active-- in reviving dormant hexachlophene research.

In light of that proposition, I invite comments by anyone on the usefullness and availability of a brain imaging technology for the effects of mitochondrial neurotoxins like hexachlorophene on myelin. It seems to me that diffusion tensor imaging (DTI) for white matter in specific brain regions ( e.g. cerebellum, hippocampus, etc.) is both diagnostic of hexachlorophene's current effects and of the potential use in testing the effectiveness of currently available therapeutic medications.

Again, I hope my research raises both interest and comments. Hexachlorophene has become the forgotten neurotoxin dispite its well researched lasting effects.

Saturday, February 11, 2006

There are over 150 articles and advertisements about hexachlorophene in the New York Times. These are two of the articles that are worth looking up. I'm sorry I don't know how to get the full articles on to the blog.

============================================================================== F.D.A. CURBS USE OF GERMICIDE TIED TO INFANT DEATHS:Hexachlorophene Productsto Be Sold on Prescription and in Weaker Strengths GERMICIDE CURBS IMPOSED BYF.D.A.By RICHARD D. LYONSSpecial to The New York Times. New York Times (1857-Current file) New York, N.Y.:Sep 23, 1972. p. 1 (2 pp.)Author(s): By RICHARD D. LYONSSpecial to The New York TimesDocument types: front_pagePublication title: New York Times (1857-Current file). New York, N.Y.: Sep 23, 1972. pg. 1, 2 pgsSource type: Historical newspaperISSN/ISBN: 03624331ProQuest document 81961073ID:Text Word Count 871Document URL: http://proquest.umi.com/ pqdweb?did=81961073&Fmt=2&clientId=23438&RQT=309&VName=HNPAbstract (Document Summary)WASHINGTON, Sept. 22 -The Food and Drug Administration put under strict controltoday the germ killer hexachlorophene. The germicide, which is commonly used inthe home, has been linked to the deaths of 39 French babies this year.===============================================================================Document 2 of 2Brain Cell Energy Found Curbed by HexachloropheneBy JANE E. BRODY. New York Times (1857-Current file) New York, N.Y.:Mar 7,1972. p. 25 (1 pp.)Author(s): By JANE E. BRODYDocument types: articlePublication title: New York Times (1857-Current file). New York, N.Y.: Mar 7, 1972. pg. 25, 1 pgsSource type: Historical newspaperISSN/ISBN: 03624331ProQuest document 79426924ID:Text Word Count 481Document URL: http://proquest.umi.com/ pqdweb?did=79426924&Fmt=2&clientId=23438&RQT=309&VName=HNPAbstract (Document Summary)Two Bronx biochemists have found that the antibacterial chemicalhexachlorophene interferes with the ability of brain cells to produce theenergy they need to function properly.=============================================================================== Copyright © 2006 ProQuest Information and Learning Company. All rights reserved. Terms & Conditions [From ProQuest Company] Please do not reply directly to this email. Use the following link to contact ProQuest: http://www.proquest.com/division/cs-support.shtml