Here is another way of assessing the presence of hexachlorophene in humans.

NeuroToxicology
Volume 28, Issue 2, March 2007, Pages 252-256
The 9th International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health

Magnetic resonance for evaluation of toxic encephalopathies: Implications from animal experiments

Hideki Igisu^{a, ,} and Yoshimasa Kinoshita^b
aInstitute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
^bDepartment of Medical Informatics, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan
Received 19 October 2005; accepted 17 May 2006. Available online 22 May 2006.

Abstract

Examinations of brain of rats intoxicated with hexachlorophene or acrylamide with ultrahigh-field (4.7 T) proton magnetic resonance (MR) showed alterations consistent with clinical pictures in humans and morphological findings in experimental animals. On the other hand, conventional biochemical analyses have revealed that ethylene oxide, methyl bromide, and acrylamide inhibit creatine kinase (CK; an enzyme catalyzing the reaction: ATP + creatine ↔ ADP + phosphocreatine) activities in the brain of animals. Thus, ³¹P MR combined with magnetization transfer may be utilized to monitor living humans (or animals) intoxicated with these chemicals by determining CK activities in the target organ.